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Can BDDCS Illuminate Targets in Drug Design?
The fact that pharmacokinetic (PK) properties of drugs influence the interaction with protein targets is a principle known for decades. The same cannot be said for the opposite – namely that targets influence PK properties of drugs. Evidence confirming this possibility is first introduced here, as w...
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| Publicado en: | Drug Discov Today |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002033/ https://ncbi.nlm.nih.gov/pubmed/31585170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2019.09.021 |
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