High-Throughput Screen for the Chemical Inhibitors of Antiapoptotic Bcl-2 Family Proteins by Multiplex Flow Cytometry

The human Bcl-2 family includes six antiapoptotic members (Bcl-2, Bcl-B, Bcl-W, Bcl-X(L), Bfl-1, and Mcl-1) and many proapoptotic members, wherein a balance between the two determines cell life or death in many physiological and disease contexts. Elevated expression of various antiapoptotic Bcl-2 me...

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Detaylı Bibliyografya
Asıl Yazarlar: Curpan, Ramona F., Simons, Peter C., Zhai, Dayong, Young, Susan M., Carter, Mark B., Bologa, Cristian G., Oprea, Tudor I., Satterthwait, Arnold C., Reed, John C., Edwards, Bruce S., Sklar, Larry A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2011
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182036/
https://ncbi.nlm.nih.gov/pubmed/21561376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0363
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