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Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems
Glucose is an essential energy source for cells. In humans, its passive diffusion through the cell membrane is facilitated by members of the glucose transporter family (GLUT, SLC2 gene family). GLUT2 transports both glucose and fructose with low affinity and plays a critical role in glucose sensing...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8253845/ https://ncbi.nlm.nih.gov/pubmed/34215797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93063-5 |
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