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Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems

Glucose is an essential energy source for cells. In humans, its passive diffusion through the cell membrane is facilitated by members of the glucose transporter family (GLUT, SLC2 gene family). GLUT2 transports both glucose and fructose with low affinity and plays a critical role in glucose sensing...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Schmidl, Sina, Ursu, Oleg, Iancu, Cristina V., Oreb, Mislav, Oprea, Tudor I., Choe, Jun-yong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253845/
https://ncbi.nlm.nih.gov/pubmed/34215797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93063-5
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