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Establishing a yeast-based screening system for discovery of human GLUT5 inhibitors and activators
Human GLUT5 is a fructose-specific transporter in the glucose transporter family (GLUT, SLC2 gene family). Its substrate-specificity and tissue-specific expression make it a promising target for treatment of diabetes, metabolic syndrome and cancer, but few GLUT5 inhibitors are known. To identify and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5524692/ https://ncbi.nlm.nih.gov/pubmed/28740135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06262-4 |
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