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Functional Expression of the Human Glucose Transporters GLUT2 and GLUT3 in Yeast Offers Novel Screening Systems for GLUT-Targeting Drugs

Human GLUT2 and GLUT3, members of the GLUT/SLC2 gene family, facilitate glucose transport in specific tissues. Their malfunction or misregulation is associated with serious diseases, including diabetes, metabolic syndrome, and cancer. Despite being promising drug targets, GLUTs have only a few speci...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Schmidl, Sina, Tamayo Rojas, Sebastian A., Iancu, Cristina V., Choe, Jun-Yong, Oreb, Mislav
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930720/
https://ncbi.nlm.nih.gov/pubmed/33681287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.598419
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