A Selective ATP-binding Cassette Sub-family G Member 2 Efflux Inhibitor Revealed Via High-Throughput Flow Cytometry

Chemotherapeutics tumor resistance is a principal reason for treatment failure and clinical and experimental data indicate that multidrug transporters such as ATP-binding Cassette (ABC) B1 and ABCG2 play a leading role by preventing cytotoxic intracellular drug concentrations. Functional efflux inhi...

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Main Authors: Strouse, J. Jacob, Ivnitski-Steele, Irena, Khawaja, Hadya M., Perez, Dominique, Ricci, Jerec, Yao, Tuanli, Weiner, Warren S., Schroeder, Chad E., Simpson, Denise S., Maki, Brooks E., Li, Kelin, Golden, Jennifer E., Foutz, Terry D., Waller, Anna, Evangelisti, Annette M., Young, Susan M., Chavez, Stephanie E., Garcia, Matthew J., Ursu, Oleg, Bologa, Cristian G., Carter, Mark B., Salas, Virginia M., Gouveia, Kristine, Tegos, George P., Oprea, Tudor I., Edwards, Bruce S., Aubé, Jeffrey, Larson, Richard S., Sklar, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623016/
https://ncbi.nlm.nih.gov/pubmed/22923785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112456875
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