A Competitive Nucleotide Binding Inhibitor: In vitro Characterization of Rab7 GTPase Inhibition

Mapping the functionality of GTPases through small molecule inhibitors represents an underexplored area in large part due to the lack of suitable compounds. Here we report on the small chemical molecule 2-(benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid (PubCh...

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Bibliografiset tiedot
Päätekijät: Agola, Jacob O., Hong, Lin, Surviladze, Zurab, Ursu, Oleg, Waller, Anna, Strouse, J. Jacob, Simpson, Denise S., Schroeder, Chad E., Oprea, Tudor I., Golden, Jennifer E., Aubé, Jeffrey, Buranda, Tione, Sklar, Larry A., Wandinger-Ness, Angela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440014/
https://ncbi.nlm.nih.gov/pubmed/22486388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb3001099
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