Functional selectivity of GPCR signaling in animals

by Zhou, Lei, Bohn, Laura M
Published in Curr Opin Cell Biol (2013)

Seeking (and Finding) Biased Ligands of the Kappa Opioid Receptor

by Bohn, Laura M., Aubé, Jeffrey
Published in ACS Med Chem Lett (2017)

Physiological and Pharmacological Implications of Beta-Arrestin Regulation

by Schmid, Cullen L., Bohn, Laura M.
Published 2008

Mu opioid receptor regulation and opiate responsiveness

by Raehal, Kirsten M., Bohn, Laura M.
Published 2005

The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics

by Raehal, Kirsten M., Bohn, Laura M.
Published 2010

Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo

by Schmid, Cullen L., Bohn, Laura M.
Published 2010

Serotonin receptor signaling and regulation via β-arrestins

by Bohn, Laura M., Schmid, Cullen L.
Published in Crit Rev Biochem Mol Biol (2010)

β-Arrestins: Regulatory Role and Therapeutic Potential in Opioid and Cannabinoid Receptor-Mediated Analgesia

by Raehal, Kirsten M., Bohn, Laura M.
Published in Handb Exp Pharmacol (2014)

Seeking Ligand Bias: Assessing GPCR Coupling to Beta-Arrestins for Drug Discovery

by Bohn, Laura M., McDonald, Patricia H.
Published 2010

Fulfilling the Promise of "Biased" G Protein–Coupled Receptor Agonism

by Luttrell, Louis M., Maudsley, Stuart, Bohn, Laura M.
Published in Mol Pharmacol (2015)

Approaches to Assess Functional Selectivity in GPCRs: Evaluating G Protein Signaling in an Endogenous Environment

by Bohn, Laura M., Zhou, Lei, Ho, Jo-Hao
Published in Methods Mol Biol (2015)

Biased agonism: An emerging paradigm in GPCR drug discovery

by Rankovic, Zoran, Brust, Tarsis F., Bohn, Laura M.
Published in Bioorg Med Chem Lett (2015)

Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo

by Schmid, Cullen L., Raehal, Kirsten M., Bohn, Laura M.
Published 2008

Mitogenic Signaling via Endogenous κ-Opioid Receptors in C6 Glioma Cells: Evidence for the Involvement of Protein Kinase C and the Mitogen-Activated Protein Kinase Signaling Cascad...

by Bohn, Laura M., Belcheva, Mariana M., Coscia, Carmine J.
Published 2000

μ-Opioid Agonist Inhibition of κ-Opioid Receptor-Stimulated Extracellular Signal-Regulated Kinase Phosphorylation Is Dynamin-Dependent in C6 Glioma Cells

by Bohn, Laura M., Belcheva, Mariana M., Coscia, Carmine J.
Published 2000

Evidence for κ- and μ-Opioid Receptor Expression in C6 Glioma Cells

by Bohn, Laura M., Belcheva, Mariana M., Coscia, Carmine J.
Published 1998

Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in βArrestin-2 Knock-Out Mice

by Bohn, Laura M., Lefkowitz, Robert J., Caron, Marc G.
Published in J Neurosci (2002)

Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics

by Grim, Travis W., Acevedo-Canabal, Agnes, Bohn, Laura M.
Published in Biol Psychiatry (2019)

Approaches to Assess Biased Signaling at the CB1R Receptor

by Laprairie, Robert B., Stahl, Edward L., Bohn, Laura M.
Published in Methods Enzymol (2017)

A Novel Method for Analyzing Extremely Biased Agonism at G Protein–Coupled Receptors

by Stahl, Edward L., Zhou, Lei, Ehlert, Frederick J., Bohn, Laura M.
Published in Mol Pharmacol (2015)