Functional selectivity of GPCR signaling in animals

Por Zhou, Lei, Bohn, Laura M
Publicado no Curr Opin Cell Biol (2013)

Physiological and Pharmacological Implications of Beta-Arrestin Regulation

Por Schmid, Cullen L., Bohn, Laura M.
Publicado em 2008

Mu opioid receptor regulation and opiate responsiveness

Por Raehal, Kirsten M., Bohn, Laura M.
Publicado em 2005

The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics

Por Raehal, Kirsten M., Bohn, Laura M.
Publicado em 2010

Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo

Por Schmid, Cullen L., Bohn, Laura M.
Publicado em 2010

Serotonin receptor signaling and regulation via β-arrestins

Por Bohn, Laura M., Schmid, Cullen L.
Publicado no Crit Rev Biochem Mol Biol (2010)

β-Arrestins: Regulatory Role and Therapeutic Potential in Opioid and Cannabinoid Receptor-Mediated Analgesia

Por Raehal, Kirsten M., Bohn, Laura M.
Publicado no Handb Exp Pharmacol (2014)

Seeking Ligand Bias: Assessing GPCR Coupling to Beta-Arrestins for Drug Discovery

Por Bohn, Laura M., McDonald, Patricia H.
Publicado em 2010

Fulfilling the Promise of "Biased" G Protein–Coupled Receptor Agonism

Por Luttrell, Louis M., Maudsley, Stuart, Bohn, Laura M.
Publicado no Mol Pharmacol (2015)

Approaches to Assess Functional Selectivity in GPCRs: Evaluating G Protein Signaling in an Endogenous Environment

Por Bohn, Laura M., Zhou, Lei, Ho, Jo-Hao
Publicado no Methods Mol Biol (2015)

Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo

Por Schmid, Cullen L., Raehal, Kirsten M., Bohn, Laura M.
Publicado em 2008

Mitogenic Signaling via Endogenous κ-Opioid Receptors in C6 Glioma Cells: Evidence for the Involvement of Protein Kinase C and the Mitogen-Activated Protein Kinase Signaling Cascad...

Por Bohn, Laura M., Belcheva, Mariana M., Coscia, Carmine J.
Publicado em 2000

μ-Opioid Agonist Inhibition of κ-Opioid Receptor-Stimulated Extracellular Signal-Regulated Kinase Phosphorylation Is Dynamin-Dependent in C6 Glioma Cells

Por Bohn, Laura M., Belcheva, Mariana M., Coscia, Carmine J.
Publicado em 2000

Evidence for κ- and μ-Opioid Receptor Expression in C6 Glioma Cells

Por Bohn, Laura M., Belcheva, Mariana M., Coscia, Carmine J.
Publicado em 1998

A Novel Method for Analyzing Extremely Biased Agonism at G Protein–Coupled Receptors

Por Stahl, Edward L., Zhou, Lei, Ehlert, Frederick J., Bohn, Laura M.
Publicado no Mol Pharmacol (2015)

Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter

Por Gainetdinov, Raul R., Mohn, Amy R., Bohn, Laura M., Caron, Marc G.
Publicado em 2001

Pharmacological characterization of a selective agonist for Bombesin Receptor Subtype - 3

Por Zhang, Li, Nothacker, Hans-Peter, Wang, Zhiwei, Bohn, Laura M, Civelli, Olivier
Publicado em 2009

Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation

Por Groer, Chad E., Schmid, Cullen L., Jaeger, Alex M., Bohn, Laura M.
Publicado em 2011

Functional Selectivity at the μ-Opioid Receptor: Implications for Understanding Opioid Analgesia and Tolerance

Por Raehal, Kirsten M., Schmid, Cullen L., Groer, Chad E., Bohn, Laura M.
Publicado em 2011

Antinociceptive Effects of Herkinorin, a MOP Receptor Agonist Derived from Salvinorin A in the Formalin Test in Rats: New Concepts in Mu Opioid Receptor Pharmacology()

Por Lamb, Kenneth, Tidgewell, Kevin, Simpson, Denise S., Bohn, Laura M., Prisinzano, Thomas E.
Publicado em 2011