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Physiological and Pharmacological Implications of Beta-Arrestin Regulation

G protein-coupled receptor-targeted drug discovery as well as “compound reassessment” requires the utilization of diverse screens to determine agonist efficacies and potencies beyond the scope of ligand binding and G protein coupling. Such efforts have arisen from extensive studies, both in cellular...

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Detalhes bibliográficos
Main Authors: Schmid, Cullen L., Bohn, Laura M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656564/
https://ncbi.nlm.nih.gov/pubmed/19100766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2008.11.005
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