Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics

由 Grim, Travis W., Acevedo-Canabal, Agnes, Bohn, Laura M.
發表在 Biol Psychiatry (2019)

Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice

由 Grim, Travis W., Wiebelhaus, Jason M., Negus, S. Stevens, Lichtman, Aron H.
發表在 Drug Alcohol Depend (2015)

Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models

由 Grim, Travis W., Ghosh, Sudeshna, Hsu, Ku-Lung, Cravatt, Benjamin F., Kinsey, Steven G., Lichtman, Aron H.
出版 2014

The effect of quinine in two bottle choice procedures in C57BL6 mice: opioid preference, somatic withdrawal, and pharmacokinetic outcomes. *

由 Grim, Travis W, Jinhong Park, Scarlet, Schmid, Cullen L., Laprairie, Robert B., Cameron, Michael, Bohn, Laura M.
發表在 Drug Alcohol Depend (2018)

Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model

由 Wilkerson, Jenny L., Donvito, Giulia, Grim, Travis W., Abdullah, Rehab A., Ogasawara, Daisuke, Cravatt, Benjamin F., Lichtman, Aron H.
發表在 J Pharmacol Exp Ther (2017)

Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain.

由 Pantouli, Fani, Grim, Travis W., Schmid, Cullen L., Acevedo-Canabal, Agnes, Kennedy, Nicole M., Cameron, Michael D., Bannister, Thomas D., Bohn, Laura M.
發表在 Neuropharmacology (2020)

Effectiveness comparisons of G-protein biased and unbiased mu opioid receptor ligands in warm water tail-withdrawal and drug discrimination in male and female rats

由 Schwienteck, Kathryn L., Faunce, Kaycee E., Rice, Kenner C., Obeng, Samuel, Zhang, Yan, Blough, Bruce E., Grim, Travis W., Negus, S. Stevens, Banks, Matthew L.
發表在 Neuropharmacology (2019)

Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497

由 Grim, Travis W., Samano, Kimberly L., Ignatowska-Jankowska, Bogna, Tao, Qing, Sim-Selly, Laura J., Selley, Dana E., Wise, Laura E., Poklis, Alphonse, Lichtman, Aron H.
發表在 J Basic Clin Physiol Pharmacol (2016)

A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal

由 Grim, Travis W., Schmid, Cullen L., Stahl, Edward L., Pantouli, Fani, Ho, Jo-Hao, Acevedo-Canabal, Agnes, Kennedy, Nicole M., Cameron, Michael D., Bannister, Thomas D., Bohn, Laura M.
發表在 Neuropsychopharmacology (2019)

Probing the CB(1) Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist

由 Laprairie, Robert B., Vemuri, Kiran, Stahl, Edward L., Korde, Anisha, Ho, Jo-Hao, Grim, Travis W., Hua, Tian, Wu, Yiran, Stevens, Raymond C., Liu, Zhi-Jie, Makriyannis, Alexandros, Bohn, Laura M.
發表在 Mol Pharmacol (2019)

The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model

由 Wilkerson, Jenny L., Niphakis, Micah J., Grim, Travis W., Mustafa, Mohammed A., Abdullah, Rehab A., Poklis, Justin L., Dewey, William L., Akbarali, Hamid, Banks, Matthew L., Wise, Laura E., Cravatt, Benjamin F., Lichtman, Aron H.
發表在 J Pharmacol Exp Ther (2016)

Δ(9)-Tetrahydrocannabinol and Endocannabinoid Degradative Enzyme Inhibitors Attenuate Intracranial Self-Stimulation in Mice

由 Wiebelhaus, Jason M., Grim, Travis W., Owens, Robert A., Lazenka, Matthew F., Sim-Selley, Laura J., Abdullah, Rehab A., Niphakis, Micah J., Vann, Robert E., Cravatt, Benjamin F., Wiley, Jenny L., Negus, S. Stevens, Lichtman, Aron H.
發表在 J Pharmacol Exp Ther (2015)

Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Sid...

由 Ghosh, Sudeshna, Kinsey, Steven G., Liu, Qing-song, Hruba, Lenka, McMahon, Lance R., Grim, Travis W., Merritt, Christina R., Wise, Laura E., Abdullah, Rehab A., Selley, Dana E., Sim-Selley, Laura J., Cravatt, Benjamin F., Lichtman, Aron H.
發表在 J Pharmacol Exp Ther (2015)

Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-G(i) Complex Structures

由 Hua, Tian, Li, Xiaoting, Wu, Lijie, Iliopoulos-Tsoutsouvas, Christos, Wang, Yuxia, Wu, Meng, Shen, Ling, Brust, Christina A., Nikas, Spyros P., Song, Feng, Song, Xiyong, Yuan, Shuguang, Sun, Qianqian, Wu, Yiran, Jiang, Shan, Grim, Travis W., Benchama, Othman, Stahl, Edward L., Zvonok, Nikolai, Zhao, Suwen, Bohn, Laura M., Makriyannis, Alexandros, Liu, Zhi-Jie
發表在 Cell (2020)

Cannabinoid CB(2) receptor ligand profiling reveals biased signalling and off-target activity

由 Soethoudt, Marjolein, Grether, Uwe, Fingerle, Jürgen, Grim, Travis W., Fezza, Filomena, de Petrocellis, Luciano, Ullmer, Christoph, Rothenhäusler, Benno, Perret, Camille, van Gils, Noortje, Finlay, David, MacDonald, Christa, Chicca, Andrea, Gens, Marianela Dalghi, Stuart, Jordyn, de Vries, Henk, Mastrangelo, Nicolina, Xia, Lizi, Alachouzos, Georgios, Baggelaar, Marc P., Martella, Andrea, Mock, Elliot D., Deng, Hui, Heitman, Laura H., Connor, Mark, Di Marzo, Vincenzo, Gertsch, Jürg, Lichtman, Aron H., Maccarrone, Mauro, Pacher, Pal, Glass, Michelle, van der Stelt, Mario
發表在 Nat Commun (2017)