A carregar...

Probing the CB(1) Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist

Cannabinoid receptor 1 (CB(1)) is a potential therapeutic target for the treatment of pain, obesity and obesity-related metabolic disorders, and addiction. The crystal structure of human CB(1) has been determined in complex with the stabilizing antagonist AM6538. In the present study, we characteriz...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Laprairie, Robert B., Vemuri, Kiran, Stahl, Edward L., Korde, Anisha, Ho, Jo-Hao, Grim, Travis W., Hua, Tian, Wu, Yiran, Stevens, Raymond C., Liu, Zhi-Jie, Makriyannis, Alexandros, Bohn, Laura M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785652/
https://ncbi.nlm.nih.gov/pubmed/31515283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.119.116483
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!