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Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics

The mu opioid receptor (MOR) is a diversely regulated target for the alleviation of pain in the clinical setting. However, untoward side effects such as tolerance, dependence, respiratory suppression, constipation, and abuse liability detract from their usefulness. Studies in genetically modified ro...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Grim, Travis W., Acevedo-Canabal, Agnes, Bohn, Laura M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919561/
https://ncbi.nlm.nih.gov/pubmed/31806082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.10.020
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