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Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics

The mu opioid receptor (MOR) is a diversely regulated target for the alleviation of pain in the clinical setting. However, untoward side effects such as tolerance, dependence, respiratory suppression, constipation, and abuse liability detract from their usefulness. Studies in genetically modified ro...

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Bibliographic Details
Published in:Biol Psychiatry
Main Authors: Grim, Travis W., Acevedo-Canabal, Agnes, Bohn, Laura M.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919561/
https://ncbi.nlm.nih.gov/pubmed/31806082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.10.020
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