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Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics

The mu opioid receptor (MOR) is a diversely regulated target for the alleviation of pain in the clinical setting. However, untoward side effects such as tolerance, dependence, respiratory suppression, constipation, and abuse liability detract from their usefulness. Studies in genetically modified ro...

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發表在:Biol Psychiatry
Main Authors: Grim, Travis W., Acevedo-Canabal, Agnes, Bohn, Laura M.
格式: Artigo
語言:Inglês
出版: 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919561/
https://ncbi.nlm.nih.gov/pubmed/31806082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.10.020
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