The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model

Serious clinical liabilities associated with the prescription of opiates for pain control include constipation, respiratory depression, pruritus, tolerance, abuse, and addiction. A recognized strategy to circumvent these side effects is to combine opioids with other antinociceptive agents. The combi...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Wilkerson, Jenny L., Niphakis, Micah J., Grim, Travis W., Mustafa, Mohammed A., Abdullah, Rehab A., Poklis, Justin L., Dewey, William L., Akbarali, Hamid, Banks, Matthew L., Wise, Laura E., Cravatt, Benjamin F., Lichtman, Aron H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Behavioral Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809319/
https://ncbi.nlm.nih.gov/pubmed/26791602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.229971
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