The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model

Serious clinical liabilities associated with the prescription of opiates for pain control include constipation, respiratory depression, pruritus, tolerance, abuse, and addiction. A recognized strategy to circumvent these side effects is to combine opioids with other antinociceptive agents. The combi...

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Bibliografiske detaljer
Udgivet i:J Pharmacol Exp Ther
Main Authors: Wilkerson, Jenny L., Niphakis, Micah J., Grim, Travis W., Mustafa, Mohammed A., Abdullah, Rehab A., Poklis, Justin L., Dewey, William L., Akbarali, Hamid, Banks, Matthew L., Wise, Laura E., Cravatt, Benjamin F., Lichtman, Aron H.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2016
Fag:
Behavioral Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809319/
https://ncbi.nlm.nih.gov/pubmed/26791602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.229971
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