Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy

Although paclitaxel effectively treats various cancers, its debilitating peripheral neuropathic pain side effects often persist long after treatment has ended. Therefore, a compelling need exists for the identification of novel pharmacologic strategies to mitigate this condition. As inhibitors of mo...

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Опубликовано в: :J Pharmacol Exp Ther
Главные авторы: Curry, Zachary A., Wilkerson, Jenny L., Bagdas, Deniz, Kyte, S. Lauren, Patel, Nipa, Donvito, Giulia, Mustafa, Mohammed A., Poklis, Justin L., Niphakis, Micah J., Hsu, Ku-Lung, Cravatt, Benjamin F., Gewirtz, David A., Damaj, M. Imad, Lichtman, Aron H.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2018
Предметы:
Behavioral Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038031/
https://ncbi.nlm.nih.gov/pubmed/29540562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.245704
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