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The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model

AIM: The present study tested whether the selective monoacylglycerol lipase (MAGL) inhibitor JZL184 would reduce allodynia and paw edema in the carrageenan test. MAIN METHODS: The anti-edematous and anti-allodynic effects of JZL184 were compared to those of PF-3845, an inhibitor of fatty acid amide...

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Autores principales: Ghosh, Sudeshna, Wise, Laura E., Chen, Yugang, Gujjar, Ramesh, Mahadevan, Anu, Cravatt, Benjamin F., Lichtman, Aron H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717616/
https://ncbi.nlm.nih.gov/pubmed/22749865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.06.020
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