Inhibition of Monoacylglycerol Lipase Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Hemorrhages in Mice

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used analgesics, but can cause gastric and esophageal hemorrhages, erosion, and ulceration. The endogenous cannabinoid (endocannabinoid; eCB) system possesses several potential targets to reduce gastric inflammatory states, including cannabi...

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Bibliographische Detailangaben
Hauptverfasser: Kinsey, Steven G., Nomura, Daniel K., O'Neal, Scott T., Long, Jonathan Z., Mahadevan, Anu, Cravatt, Benjamin F., Grider, John R., Lichtman, Aron H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2011
Schlagworte:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164340/
https://ncbi.nlm.nih.gov/pubmed/21659471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.175778
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