Biased agonism: An emerging paradigm in GPCR drug discovery

by Rankovic, Zoran, Brust, Tarsis F., Bohn, Laura M.
Published in Bioorg Med Chem Lett (2015)

Evaluating and evolving a screening library in academia: the St. Jude approach

by Nishiguchi, Gisele, Das, Sourav, Ochoada, Jason, Long, Heather, Lee, Richard E., Rankovic, Zoran, Shelat, Anang A.
Published in Drug Discov Today (2021)

PDTM-02. TARGETING THE RB PATHWAY IN MEDULLOBLASTOMA

by Jonchere, Barbara, Stripay, Jennifer, Pribnow, Allison, Zindy, Frederique, Min, Jaeki, Freeman, Burgess, Shelat, Anang, Rankovic, Zoran, Roussel, Martine
Published in Neuro Oncol (2019)

Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss

by Hazlitt, Robert A., Teitz, Tal, Bonga, Justine D., Fang, Jie, Diao, Shiyong, Iconaru, Luigi, Yang, Lei, Goktug, Asli N., Currier, Duane G., Chen, Taosheng, Rankovic, Zoran, Min, Jaeki, Zuo, Jian
Published in J Med Chem (2018)

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases

by Yang, Seung Wook, Huang, Xin, Lin, Wenwei, Min, Jaeki, Miller, Darcie J., Mayasundari, Anand, Rodrigues, Patrick, Griffith, Elizabeth C., Gee, Clifford T., Li, Lei, Li, Wei, Lee, Richard E., Rankovic, Zoran, Chen, Taosheng, Potts, Patrick Ryan
Published in Nat Commun (2020)

Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators

by Nishiguchi, Gisele, Keramatnia, Fatemeh, Min, Jaeki, Chang, Yunchao, Jonchere, Barbara, Das, Sourav, Actis, Marisa, Price, Jeanine, Chepyala, Divyabharathi, Young, Brandon, McGowan, Kevin, Slavish, P. Jake, Mayasundari, Anand, Jarusiewicz, Jamie A., Yang, Lei, Li, Yong, Fu, Xiang, Garrett, Shalandus H., Papizan, James B., Kodali, Kiran, Peng, Junmin, Pruett Miller, Shondra M., Roussel, Martine F., Mullighan, Charles, Fischer, Marcus, Rankovic, Zoran
Published in J Med Chem (2021)

17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma

by Singh, Shivendra, Abu-Zaid, Ahmed, Lin, Wenwei, Low, Jonathan, Abdolvahabi, Alireza, Jin, Hongjian, Wu, Qiong, Cooke, Bailey, Fang, Jie, Bowling, John, Vaithiyalingam, Sivaraja, Currier, Duane, Yun, Mi-Kyung, Fernando, Dinesh M., Maier, Julie, Tillman, Heather, Bulsara, Purva, Lu, Zhaohua, Das, Sourav, Shelat, Anang, Li, Zhenmei, Young, Brandon, Lee, Richard, Rankovic, Zoran, Murphy, Andrew J., White, Stephen W., Davidoff, Andrew M., Chen, Taosheng, Yang, Jun
Published in iScience (2020)

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

by He, Chen, Xu, Ke, Zhu, Xiaoyan, Dunphy, Paige S., Gudenas, Brian, Lin, Wenwei, Twarog, Nathaniel, Hover, Laura D., Kwon, Chang-Hyuk, Kasper, Lawryn H., Zhang, Junyuan, Li, Xiaoyu, Dalton, James, Jonchere, Barbara, Mercer, Kimberly S., Currier, Duane G., Caufield, William, Wang, Yingzhe, Xie, Jia, Broniscer, Alberto, Wetmore, Cynthia, Upadhyaya, Santhosh A., Qaddoumi, Ibrahim, Klimo, Paul, Boop, Frederick, Gajjar, Amar, Zhang, Jinghui, Orr, Brent A., Robinson, Giles W., Monje, Michelle, Freeman III, Burgess B., Roussel, Martine F., Northcott, Paul A., Chen, Taosheng, Rankovic, Zoran, Wu, Gang, Chiang, Jason, Tinkle, Christopher L., Shelat, Anang A., Baker, Suzanne J.
Published in Nat Commun (2021)