PDTM-02. TARGETING THE RB PATHWAY IN MEDULLOBLASTOMA

Medulloblastoma (MB), the most common malignant pediatric brain tumor, is classified into four major molecularly and histopathologically distinct subgroups, among which MYC-driven Group 3 MBs confer a poor prognosis. The Cyclin D/CDK4/CDK6/RB pathway is frequently deregulated in MB leading to uncont...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Jonchere, Barbara, Stripay, Jennifer, Pribnow, Allison, Zindy, Frederique, Min, Jaeki, Freeman, Burgess, Shelat, Anang, Rankovic, Zoran, Roussel, Martine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Pediatric Tumors
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847011/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.778
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