Development of an Oral Form of Azacytidine: 2′3′5′Triacetyl-5-Azacytidine

by Ziemba, Amy, Hayes, Eugene, Freeman, Burgess B., Ye, Tao, Pizzorno, Giuseppe
Published 2011

Optimization of Antitumor Modulators of Pre-mRNA Splicing

by Lagisetti, Chandraiah, Palacios, Gustavo, Goronga, Tinopiwa, Freeman, Burgess, Caufield, William, Webb, Thomas R.
Published 2013

Using plasma topotecan pharmacokinetics to estimate topotecan exposure in cerebrospinal fluid of children with medulloblastoma

by Freeman, Burgess B., Iacono, Lisa C., Panetta, John C., Gajjar, Amar, Stewart, Clinton F.
Published 2006

PDTM-02. TARGETING THE RB PATHWAY IN MEDULLOBLASTOMA

by Jonchere, Barbara, Stripay, Jennifer, Pribnow, Allison, Zindy, Frederique, Min, Jaeki, Freeman, Burgess, Shelat, Anang, Rankovic, Zoran, Roussel, Martine
Published in Neuro Oncol (2019)

PCM-06 ACCURATE PRECLINICAL TRIALS OF NEW EPENDYMOMA THERAPIES

by Boulos, Nidal, Dapper, Jason, Patel, Yogesh, DeCuypere, Michael, Bianski, Brandon, Merchant, Thomas, Freeman, Burgess, Guy, Rodney, Stewart, Clinton, Wright, Karen, Gilbertson, Richard
Published in Neuro Oncol (2016)

Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study

by Patel, Yogesh T., Jacus, Megan O., Davis, Abigail D., Boulos, Nidal, Turner, David C., Vuppala, Pradeep K., Freeman, Burgess B., Gilbertson, Richard J., Stewart, Clinton F.
Published in Drug Metab Dispos (2016)

Pharmacokinetics and Efficacy of the Spleen Tyrosine Kinase Inhibitor R406 after Ocular Delivery for Retinoblastoma

by Pritchard, Eleanor M., Stewart, Elizabeth, Zhu, Fangyi, Bradley, Cori, Griffiths, Lyra, Yang, Lei, Suryadevara, Praveen Kumar, Zhang, Jiakun, Freeman, Burgess B., Guy, R. Kiplin, Dyer, Michael A.
Published 2014

Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors

by Morfouace, Marie, Nimmervoll, Birgit, Boulos, Nidal, Patel, Yogesh T., Shelat, Anang, Freeman, Burgess B., Robinson, Giles W., Wright, Karen, Gajjar, Amar, Stewart, Clinton F., Gilbertson, Richard J., Roussel, Martine F.
Published in J Neurooncol (2015)

Preclinical examination of clofarabine in pediatric ependymoma: Intratumoral concentrations insufficient to warrant further study

by Patel, Yogesh T., Jacus, Megan O., Boulos, Nidal, Dapper, Jason D., Davis, Abigail D., Vuppala, Pradeep K., Freeman, Burgess B., Mohankumar, Kumarasamypet M., Throm, Stacy L., Gilbertson, Richard J., Stewart, Clinton F.
Published in Cancer Chemother Pharmacol (2015)

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

by Chen, Yizhe, Zhu, Fangyi, Hammill, Jared, Holbrook, Gloria, Yang, Lei, Freeman, Burgess, White, Karen L., Shackleford, David M., O’Loughlin, Kathleen G., Charman, Susan A., Mirsalis, Jon C., Guy, R. Kiplin
Published in Malar J (2021)

Population Pharmacokinetics of Bevacizumab in Children with Osteosarcoma: Implications for Dosing

by Turner, David C., Navid, Fariba, Daw, Najat C., Mao, Shenghua, Wu, Jianrong, Santana, Victor M., Neel, Michael, Rao, Bhaskar, Willert, Jennifer Reikes, Loeb, David M., Harstead, K. Elaine, Throm, Stacy L., Freeman, Burgess B., Stewart, Clinton F.
Published 2014

Restoring auditory cortex plasticity in adult mice by restricting thalamic adenosine signaling()

by Blundon, Jay A., Roy, Noah C., Teubner, Brett J. W., Yu, Jing, Eom, Tae-Yeon, Sample, K. Jake, Pani, Amar, Smeyne, Richard J., Han, Seung Baek, Kerekes, Ryan A, Rose, Derek C., Hackett, Troy A., Vuppala, Pradeep K., Freeman, Burgess B., Zakharenko, Stanislav S.
Published in Science (2017)

Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma

by Morfouace, Marie, Shelat, Anang, Jacus, Megan, Freeman, Burgess B., Turner, David, Robinson, Sarah, Zindy, Frederique, Wang, Yong-Dong, Finkelstein, David, Ayrault, Olivier, Bihannic, Laure, Li, Xiao-Nan, Olson, James M., Robinson, Giles W., Guy, R. Kiplin, Stewart, Clinton F., Gajjar, Amar, Roussel, Martine F.
Published 2014

Establishing A Preclinical Multidisciplinary Board for Brain Tumors

by Nimmervoll, Birgit V., Boulos, Nidal, Bianski, Brandon, Dapper, Jason, DeCuypere, Michael, Shelat, Anang, Terranova, Sabrina, Terhune, Hope E., Gajjar, Amar, Patel, Yogesh T., Freeman, Burgess B., Onar-Thomas, Arzu, Stewart, Clinton F., Roussel, Martine F., Guy, R. Kipling, Merchant, Thomas E., Calabrese, Christopher, Wright, Karen D., Gilbertson, Richard J.
Published in Clin Cancer Res (2018)

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss

by Teitz, Tal, Fang, Jie, Goktug, Asli N., Bonga, Justine D., Diao, Shiyong, Hazlitt, Robert A., Iconaru, Luigi, Morfouace, Marie, Currier, Duane, Zhou, Yinmei, Umans, Robyn A., Taylor, Michael R., Cheng, Cheng, Min, Jaeki, Freeman, Burgess, Peng, Junmin, Roussel, Martine F., Kriwacki, Richard, Guy, R. Kiplin, Chen, Taosheng, Zuo, Jian
Published in J Exp Med (2018)

Targeting the DNA Repair Pathway in Ewing Sarcoma

by Stewart, Elizabeth, Goshorn, Ross, Bradley, Cori, Griffiths, Lyra M., Benavente, Claudia, Twarog, Nathaniel R., Miller, Gregory M., Caufield, William, Freeman, Burgess B., Bahrami, Armita, Pappo, Alberto, Wu, Jianrong, Loh, Amos, Karlström, Åsa, Calabrese, Chris, Gordon, Brittney, Tsurkan, Lyudmila, Hatfield, M. Jason, Potter, Philip M., Snyder, Scott, Thiagarajan, Suresh, Shirinifard, Abbas, Sablauer, Andras, Shelat, Anang A., Dyer, Michael A.
Published in Cell Rep (2014)

Orthotopic Patient-Derived Xenografts of Pediatric Solid Tumors

by Stewart, Elizabeth, Federico, Sara M., Chen, Xiang, Shelat, Anang A., Bradley, Cori, Gordon, Brittney, Karlstrom, Asa, Twarog, Nathaniel R., Clay, Michael R., Bahrami, Armita, Freeman, Burgess B., Xu, Beisi, Zhou, Xin, Wu, Jianrong, Honnell, Victoria, Ocarz, Monica, Blankenship, Kaley, Dapper, Jason, Mardis, Elaine R., Wilson, Richard K., Downing, James, Zhang, Jinghui, Easton, John, Pappo, Alberto, Dyer, Michael A.
Published in Nature (2017)

Selective Modulation of the Androgen Receptor Activation Function-2 Domain Rescues Degeneration in Spinal Bulbar Muscular Atrophy

by Badders, Nisha M, Korff, Ane, Miranda, Helen C, Vuppala, Pradeep K, Smith, Rebecca B, Winborn, Brett J, Quemin, Emmanuelle R, Sopher, Bryce L, Dearman, Jennifer, Messing, James, Kim, Nam Chul, Moore, Jennifer, Freibaum, Brian D, Kanagaraj, Anderson P, Fan, Baochang, Tillman, Heather, Chen, Ping-Chung, Wang, Yingzhe, Freeman, Burgess B, Li, Yimei, Kim, Hong Joo, La Spada, Albert R, Taylor, J Paul
Published in Nat Med (2018)

Modeling and targeting of erythroleukemia by hematopoietic genome editing

by Iacobucci, Ilaria, Qu, Chunxu, Varotto, Elena, Janke, Laura J., Yang, Xu, Seth, Aman, Shelat, Anang, Friske, Jake D., Fukano, Reiji, Yu, Jiyang, Freeman, Burgess B., Kennedy, James A., Sperling, Adam S., Zheng, Rena, Wang, Yingzhe, Jogiraju, Harini, Dickerson, Kirsten M., Payne-Turner, Debbie, Morris, Sarah M., Hollis, Emily S., Ghosn, Nina, Haggard, Georgia E., Lindsley, R. Coleman, Ebert, Benjamin L., Mullighan, Charles G.
Published in Blood (2021)

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

by Diouf, Barthelemy, Wing, Claudia, Panetta, John C., Eddins, Donnie, Lin, Wenwei, Yang, Wenjian, Fan, Yiping, Pei, Deqing, Cheng, Cheng, Delaney, Shannon M., Zhang, Wei, Bonten, Erik J., Crews, Kristine R., Paugh, Steven W., Li, Lie, Freeman, Burgess B., Autry, Robert J., Beard, Jordan A., Ferguson, Daniel C., Janke, Laura J., Ness, Kirsten K., Chen, Taosheng, Zakharenko, Stanislav S., Jeha, Sima, Pui, Ching‐Hon, Relling, Mary V., Eileen Dolan, M., Evans, William E.
Published in Clin Transl Sci (2021)