Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

BACKGROUND: The ongoing global malaria eradication campaign requires development of potent, safe, and cost-effective drugs lacking cross-resistance with existing chemotherapies. One critical step in drug development is selecting a suitable clinical candidate from late leads. The process used to sele...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Chen, Yizhe, Zhu, Fangyi, Hammill, Jared, Holbrook, Gloria, Yang, Lei, Freeman, Burgess, White, Karen L., Shackleford, David M., O’Loughlin, Kathleen G., Charman, Susan A., Mirsalis, Jon C., Guy, R. Kiplin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893776/
https://ncbi.nlm.nih.gov/pubmed/33608015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-021-03617-1
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