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Pharmacokinetics and Dose-range Finding Toxicity of a Novel anti-HIV Active Integrase Inhibitor

Integration of viral DNA into human chromosomal DNA catalyzed by HIV integrase represents the “point of no return” in HIV infection. For this reason, HIV integrase is considered a crucial target in the development of new anti-HIV therapeutic agents. We have discovered a novel HIV integrase inhibitor...

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Detalhes bibliográficos
Main Authors: Nair, Vasu, Okello, Maurice, Mishra, Sanjay, Mirsalis, Jon, O’Loughlin, Kathleen, Zhong, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101043/
https://ncbi.nlm.nih.gov/pubmed/24821255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.05.001
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