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Solid-state tautomeric structure and invariom refinement of a novel and potent HIV integrase inhibitor

The conformation and tautomeric structure of (Z)-4-[5-(2,6-difluoro­benzyl)-1-(2-fluoro­benzyl)-2-oxo-1,2-dihydro­pyridin-3-yl]-4-hy­droxy-2-oxo-N-(2-oxopyrrolidin-1-yl)but-3-enamide, C(27)H(22)F(3)N(3)O(5), in the solid state has been resolved by single-crystal X-ray crystallography. The electron d...

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Detalhes bibliográficos
Main Authors: Bacsa, John, Okello, Maurice, Singh, Pankaj, Nair, Vasu
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589111/
https://ncbi.nlm.nih.gov/pubmed/23459357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0108270113003806
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