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Preclinical examination of clofarabine in pediatric ependymoma: Intratumoral concentrations insufficient to warrant further study
Clofarabine, a deoxyadenosine analog, was an active anticancer drug in our in vitro high-throughput screening against mouse ependymoma neurospheres. To characterize the clofarabine disposition in mice for further preclinical efficacy studies, we evaluated the plasma and central nervous system (CNS)...
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| Publicado no: | Cancer Chemother Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4420645/ https://ncbi.nlm.nih.gov/pubmed/25724157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2713-z |
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