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Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma

BACKGROUND: We report a phase I study to examine the pharmacokinetics, safety, and recommended dosage of weekly intravenous bolus 5-fluorouracil (5-FU) in children and young adults with recurrent ependymoma. METHODS: Patients 22 years of age or less with recurrent ependymoma were treated with bolus...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wright, Karen D., Daryani, Vinay M., Turner, David C., Onar-Thomas, Arzu, Boulos, Nidal, Orr, Brent A., Gilbertson, Richard J., Stewart, Clinton F., Gajjar, Amar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633933/
https://ncbi.nlm.nih.gov/pubmed/26541630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov181
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