Lack of efficacy of bevacizumab + irinotecan in cases of pediatric recurrent ependymoma—a Pediatric Brain Tumor Consortium study

A phase II study of bevacizumab (BVZ) plus irinotecan (CPT-11) was conducted in cases of pediatric recurrent ependymoma (EPN) to estimate sustained objective response rate and progression-free survival (PFS). Eligible patients received 2 doses of single-agent BVZ intravenously (10 mg/kg) 2 weeks apa...

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Bibliographische Detailangaben
Hauptverfasser: Gururangan, Sridharan, Fangusaro, Jason, Young Poussaint, Tina, Onar-Thomas, Arzu, Gilbertson, Richard J., Vajapeyam, Sridhar, Gajjar, Amar, Goldman, Stewart, Friedman, Henry S., Packer, Roger J., Boyett, James M., Kun, Larry E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Clinical Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480265/
https://ncbi.nlm.nih.gov/pubmed/23019233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos213
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