Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas—a Pediatric Brain Tumor Consortium study

BACKGROUND: A phase II study of bevacizumab (BVZ) plus irinotecan (CPT-11) was conducted in children with recurrent low-grade glioma to measure sustained response and/or stable disease lasting ≥6 months and progression-free survival. METHODS: Thirty-five evaluable patients received 2 doses (10 mg/kg...

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Detalhes bibliográficos
Main Authors: Gururangan, Sridharan, Fangusaro, Jason, Poussaint, Tina Young, McLendon, Roger E., Onar-Thomas, Arzu, Wu, Shengjie, Packer, Roger J., Banerjee, Anu, Gilbertson, Richard J., Fahey, Frederic, Vajapeyam, Sridhar, Jakacki, Regina, Gajjar, Amar, Goldman, Stewart, Pollack, Ian F., Friedman, Henry S., Boyett, James M., Fouladi, Maryam, Kun, Larry E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Pediatric Neuro-oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895377/
https://ncbi.nlm.nih.gov/pubmed/24311632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not154
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