Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas—a Pediatric Brain Tumor Consortium study

BACKGROUND: A phase II study of bevacizumab (BVZ) plus irinotecan (CPT-11) was conducted in children with recurrent low-grade glioma to measure sustained response and/or stable disease lasting ≥6 months and progression-free survival. METHODS: Thirty-five evaluable patients received 2 doses (10 mg/kg...

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Dades bibliogràfiques
Autors principals: Gururangan, Sridharan, Fangusaro, Jason, Poussaint, Tina Young, McLendon, Roger E., Onar-Thomas, Arzu, Wu, Shengjie, Packer, Roger J., Banerjee, Anu, Gilbertson, Richard J., Fahey, Frederic, Vajapeyam, Sridhar, Jakacki, Regina, Gajjar, Amar, Goldman, Stewart, Pollack, Ian F., Friedman, Henry S., Boyett, James M., Fouladi, Maryam, Kun, Larry E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Pediatric Neuro-oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895377/
https://ncbi.nlm.nih.gov/pubmed/24311632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not154
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