Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas—a Pediatric Brain Tumor Consortium study

BACKGROUND: A phase II study of bevacizumab (BVZ) plus irinotecan (CPT-11) was conducted in children with recurrent low-grade glioma to measure sustained response and/or stable disease lasting ≥6 months and progression-free survival. METHODS: Thirty-five evaluable patients received 2 doses (10 mg/kg...

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Detalles Bibliográficos
Autores principales: Gururangan, Sridharan, Fangusaro, Jason, Poussaint, Tina Young, McLendon, Roger E., Onar-Thomas, Arzu, Wu, Shengjie, Packer, Roger J., Banerjee, Anu, Gilbertson, Richard J., Fahey, Frederic, Vajapeyam, Sridhar, Jakacki, Regina, Gajjar, Amar, Goldman, Stewart, Pollack, Ian F., Friedman, Henry S., Boyett, James M., Fouladi, Maryam, Kun, Larry E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
Materias:
Pediatric Neuro-oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895377/
https://ncbi.nlm.nih.gov/pubmed/24311632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not154
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