Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas—a Pediatric Brain Tumor Consortium study

BACKGROUND: A phase II study of bevacizumab (BVZ) plus irinotecan (CPT-11) was conducted in children with recurrent low-grade glioma to measure sustained response and/or stable disease lasting ≥6 months and progression-free survival. METHODS: Thirty-five evaluable patients received 2 doses (10 mg/kg...

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Bibliografiska uppgifter
Huvudupphovsmän: Gururangan, Sridharan, Fangusaro, Jason, Poussaint, Tina Young, McLendon, Roger E., Onar-Thomas, Arzu, Wu, Shengjie, Packer, Roger J., Banerjee, Anu, Gilbertson, Richard J., Fahey, Frederic, Vajapeyam, Sridhar, Jakacki, Regina, Gajjar, Amar, Goldman, Stewart, Pollack, Ian F., Friedman, Henry S., Boyett, James M., Fouladi, Maryam, Kun, Larry E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Pediatric Neuro-oncology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895377/
https://ncbi.nlm.nih.gov/pubmed/24311632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not154
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