Bevacizumab (BVZ)-Associated Toxicities in Children with Recurrent Central Nervous System (CNS) Tumors treated with BVZ and Irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022)

BACKGROUND: The incidence and spectrum of acute toxicities related to the use of bevacizumab (BVZ)-containing regimens in children are largely unknown. We report on the adverse events in a recently completed large phase II trial of BVZ plus irinotecan (CPT-11) in children with recurrent central nerv...

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Detalhes bibliográficos
Main Authors: Fangusaro, Jason, Gururangan, Sridharan, Young-Poussaint, Tina, McLendon, Roger E., Onar-Thomas, Arzu, Warren, Katherine E., Wu, Shengjie, Packer, Roger J., Banerjee, Anu, Gilbertson, Richard J., Jakacki, Regina, Gajjar, Amar, Goldman, Stewart, Pollack, Ian F., Friedman, Henry S., Boyett, James M., Kun, Larry E., Fouladi, Maryam
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835419/
https://ncbi.nlm.nih.gov/pubmed/24104527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28343
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