An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

Cancers are characterized by non-random, chromosome copy number alterations that presumably contain oncogenes and tumor–suppressor genes (TSGs). The affected loci are often large, making it difficult to pinpoint which genes are driving the cancer. Here, we report a cross-species in vivo screen of 84...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Mohankumar, Kumarasamypet M., Currle, David S., White, Elsie, Boulos, Nidal, Dapper, Jason, Eden, Christopher, Nimmervoll, Birgit, Thiruvenkatam, Radhika, Connelly, Michele, Kranenburg, Tanya A., Neale, Geoffrey, Olsen, Scott, Wang, Yong-Dong, Finkelstein, David, Wright, Karen, Gupta, Kirti, Ellison, David W., Thomas, Arzu Onar, Gilbertson, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520751/
https://ncbi.nlm.nih.gov/pubmed/26075792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3323
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