An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

Cancers are characterized by non-random, chromosome copy number alterations that presumably contain oncogenes and tumor–suppressor genes (TSGs). The affected loci are often large, making it difficult to pinpoint which genes are driving the cancer. Here, we report a cross-species in vivo screen of 84...

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Bibliografski detalji
Izdano u:Nat Genet
Glavni autori: Mohankumar, Kumarasamypet M., Currle, David S., White, Elsie, Boulos, Nidal, Dapper, Jason, Eden, Christopher, Nimmervoll, Birgit, Thiruvenkatam, Radhika, Connelly, Michele, Kranenburg, Tanya A., Neale, Geoffrey, Olsen, Scott, Wang, Yong-Dong, Finkelstein, David, Wright, Karen, Gupta, Kirti, Ellison, David W., Thomas, Arzu Onar, Gilbertson, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520751/
https://ncbi.nlm.nih.gov/pubmed/26075792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3323
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