An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

Cancers are characterized by non-random, chromosome copy number alterations that presumably contain oncogenes and tumor–suppressor genes (TSGs). The affected loci are often large, making it difficult to pinpoint which genes are driving the cancer. Here, we report a cross-species in vivo screen of 84...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nat Genet
Hauptverfasser: Mohankumar, Kumarasamypet M., Currle, David S., White, Elsie, Boulos, Nidal, Dapper, Jason, Eden, Christopher, Nimmervoll, Birgit, Thiruvenkatam, Radhika, Connelly, Michele, Kranenburg, Tanya A., Neale, Geoffrey, Olsen, Scott, Wang, Yong-Dong, Finkelstein, David, Wright, Karen, Gupta, Kirti, Ellison, David W., Thomas, Arzu Onar, Gilbertson, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520751/
https://ncbi.nlm.nih.gov/pubmed/26075792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3323
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge