Targeting the DNA Repair Pathway in Ewing Sarcoma

Ewing sarcoma (EWS) is a tumor of the bone and soft-tissue that primarily affects adolescents and young adults. With current therapies, 70% of patients with localized disease survive, but patients with metastatic or recurrent disease have a poor outcome. We found that EWS cell lines are defective in...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Stewart, Elizabeth, Goshorn, Ross, Bradley, Cori, Griffiths, Lyra M., Benavente, Claudia, Twarog, Nathaniel R., Miller, Gregory M., Caufield, William, Freeman, Burgess B., Bahrami, Armita, Pappo, Alberto, Wu, Jianrong, Loh, Amos, Karlström, Åsa, Calabrese, Chris, Gordon, Brittney, Tsurkan, Lyudmila, Hatfield, M. Jason, Potter, Philip M., Snyder, Scott, Thiagarajan, Suresh, Shirinifard, Abbas, Sablauer, Andras, Shelat, Anang A., Dyer, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386669/
https://ncbi.nlm.nih.gov/pubmed/25437539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.028
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