Fragment Screening and Druggability Assessment for the CBP/p300 KIX Domain Via Protein Observed (19)F NMR

por Gee, Clifford T., Koleski, Edward J., Pomerantz, William C. K.
Publicado en Angew Chem Int Ed Engl (2015)

Paramagnetic relaxation enhancement for protein-observed (19)F NMR as an enabling approach for efficient fragment screening

por Hawk, Laura M.L., Gee, Clifford T., Urick, Andrew K., Hu, Haitao, Pomerantz, William C.K.
Publicado en RSC Adv (2016)

Dual Labeling of the CBP/p300 KIX domain for (19)F NMR leads to identification of a new small molecule binding site

por Gee, Clifford T., Arntson, Keith E., Koleski, Edward J., Staebell, Rachel Lynn, Pomerantz, William C.K.
Publicado en Chembiochem (2018)

Protein-observed (19)F-NMR for fragment screening, affinity quantification and druggability assessment

por Gee, Clifford T, Arntson, Keith E, Urick, Andrew K, Mishra, Neeraj K, Hawk, Laura M L, Wisniewski, Andrea J, Pomerantz, William C K
Publicado en Nat Protoc (2016)

Mechanisms of resistance associated with the inhibition of the dehydration step of FAS-II in Mycobacterium tuberculosis

por Grzegorzewicz, Anna E., Gee, Clifford, Das, Sourav, Liu, Jiuyu, Belardinelli, Juan Manuel, Jones, Victoria, McNeil, Michael R., Lee, Richard E., Jackson, Mary
Publicado en ACS Infect Dis (2019)

Oxygen Sensing with Perfluorocarbon-Loaded Ultraporous Mesostructured Silica Nanoparticles

por Lee, Amani L., Gee, Clifford T., Weegman, Bradley P., Einstein, Samuel A., Juelfs, Adam, Ring, Hattie L., Hurley, Katie R., Egger, Sam M., Swindlehurst, Garrett, Garwood, Michael, Pomerantz, William C. K., Haynes, Christy L.
Publicado en ACS Nano (2017)

Discovery and characterization of the antimetabolite action of thioacetamide-linked 1,2,3-triazoles as disruptors of cysteine biosynthesis in Gram-negative bacteria

por Wallace, Miranda J., Dharuman, Suresh, Fernando, Dinesh M., Reeve, Stephanie M., Gee, Clifford T., Yao, Jiangwei, Griffith, Elizabeth C., Phelps, Gregory A., Wright, William C., Elmore, John M., Lee, Robin B., Chen, Taosheng, Lee, Richard E.
Publicado en ACS Infect Dis (2020)

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases

por Yang, Seung Wook, Huang, Xin, Lin, Wenwei, Min, Jaeki, Miller, Darcie J., Mayasundari, Anand, Rodrigues, Patrick, Griffith, Elizabeth C., Gee, Clifford T., Li, Lei, Li, Wei, Lee, Richard E., Rankovic, Zoran, Chen, Taosheng, Potts, Patrick Ryan
Publicado en Nat Commun (2020)

BET Bromodomain Inhibitors With One-step Synthesis Discovered from Virtual Screen

por Ayoub, Alex M., Hawk, Laura M. L., Herzig, Ryan J., Jiang, Jiewei, Wisniewski, Andrea J., Gee, Clifford T., Zhao, Peiliang, Zhu, Jin-Yi, Berndt, Norbert, Offei-Addo, Nana K., Scott, Thomas G., Qi, Jun, Bradner, James E., Ward, Timothy R., Schönbrunn, Ernst, Georg, Gunda I., Pomerantz, William C.K.
Publicado en J Med Chem (2017)