Mutual information identifies sequence positions conserved within the nuclear receptor superfamily: approach reveals functionally important regions for DNA binding specificity

Por Willis, Scooter, Griffin, Patrick R.
Publicado em 2011

Targeting the Peroxisome Proliferator-Activated Receptor-γ to Counter the Inflammatory Milieu in Obesity

Por Corzo, Cesar, Griffin, Patrick R.
Publicado em 2013

A Java API for working with PubChem datasets

Por Southern, Mark R., Griffin, Patrick R.
Publicado em 2011

Development of Novel Pharmacotherapeutics for Tobacco Dependence: Progress and Future Directions

Por Harmey, Dympna, Griffin, Patrick R., Kenny, Paul J.
Publicado em 2012

HDX-MS Guided Drug Discovery: Small Molecules and Biopharmaceuticals

Por Marciano, David P., Dharmarajan, Venkatasubramanian, Griffin, Patrick R.
Publicado no Curr Opin Struct Biol (2014)

Targeting Orphan Nuclear Receptors for Treatment of Metabolic Diseases and Autoimmunity

Por Burris, Thomas P., Busby, Scott A., Griffin, Patrick R.
Publicado em 2012

Automated Hydrogen/Deuterium Exchange Electron Transfer Dissociation High Resolution Mass Spectrometry Measured at Single-Amide Resolution

Por Landgraf, Rachelle R., Chalmers, Michael J., Griffin, Patrick R.
Publicado em 2011

Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics

Por Solt, Laura A., Griffin, Patrick R., Burris, Thomas P.
Publicado no Curr Opin Lipidol (2010)

PubChem promiscuity: a web resource for gathering compound promiscuity data from PubChem

Por Canny, Stephanie A., Cruz, Yasel, Southern, Mark R., Griffin, Patrick R.
Publicado em 2012

Combined Ligand- and Structure-based Virtual Screening Protocol Identifies Novel Submicromolar PPARγ Partial Agonists Title

Por Vidović, Dušica, Busby, Scott A., Griffin, Patrick R., Schürer, Stephan C.
Publicado em 2011

Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles

Por Kirschke, Elaine, Goswami, Devrishi, Southworth, Daniel, Griffin, Patrick R., Agard, David
Publicado em 2014

Pharmacological repression of RORγ is therapeutic in the collagen-induced arthritis experimental model

Por Chang, Mi Ra, Lyda, Brent, Kamenecka, Theodore M., Griffin, Patrick R.
Publicado no Arthritis Rheumatol (2014)

Identification of Bexarotene as a PPARγ Antagonist with HDX

Por Marciano, David P., Kuruvilla, Dana S., Pascal, Bruce D., Griffin, Patrick R.
Publicado no PPAR Res (2015)

The therapeutic potential of RORγ modulators in the treatment of human disease

Por Chang, Mi Ra, Goswami, Devrishi, Mercer, Becky A, Griffin, Patrick R
Publicado no J Exp Pharmacol (2012)

HD Desktop: an integrated platform for the analysis and visualization of H/D exchange data

Por Pascal, Bruce D., Chalmers, Michael J., Busby, Scott A., Griffin, Patrick R.
Publicado em 2008

A Second Class of Nuclear Receptors for Oxysterols: Regulation of RORα and RORγ activity by 24S-Hydroxycholesterol (Cerebrosterol)

Por Wang, Yongjun, Kumar, Naresh, Crumbley, Christine, Griffin, Patrick R., Burris, Thomas P.
Publicado em 2010

Structural Basis for Ligand Regulation of the Fatty Acid-binding Protein 5, Peroxisome Proliferator-activated Receptor β/δ (FABP5-PPARβ/δ) Signaling Pathway

Por Armstrong, Eric H., Goswami, Devrishi, Griffin, Patrick R., Noy, Noa, Ortlund, Eric A.
Publicado em 2014

Identification and function of conformational dynamics in the multidomain GTPase dynamin

Por Srinivasan, Saipraveen, Dharmarajan, Venkatasubramanian, Reed, Dana Kim, Griffin, Patrick R, Schmid, Sandra L
Publicado no EMBO J (2016)

Divergent Sequence Tunes Ligand Sensitivity in Phospholipid-regulated Hormone Receptors

Por Musille, Paul M., Pathak, Manish, Lauer, Janelle L., Griffin, Patrick R., Ortlund, Eric A.
Publicado em 2013

A Two-Stage Differential Hydrogen Deuterium Exchange Method for the Rapid Characterization of Protein/Ligand Interactions

Por Chalmers, Michael J., Busby, Scott A., Pascal, Bruce D., Southern, Mark R., Griffin, Patrick R.
Publicado em 2007