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Pharmacological repression of RORγ is therapeutic in the collagen-induced arthritis experimental model
OBJECTIVE: The nuclear receptor RORγ (RAR-related orphan receptor gamma; T cell specific isoform is RORγt) is a key regulator of T(H)17 cell differentiation controlling the production of the inflammatory cytokine IL17. Further it has been shown that LPS stimulation of monocytes leads to induction of...
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| Published in: | Arthritis Rheumatol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474185/ https://ncbi.nlm.nih.gov/pubmed/24574218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38272 |
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