Synthesis of 2-aryl-2H-tetrazoles via a regioselective [3+2] cycloaddition reaction

par Patouret, Remi, Kamenecka, Theodore M.
Publié dans Tetrahedron Lett (2016)

Multigram-scale Synthesis of Enantiopure 3,3-Difluoroproline

par Doebelin, Christelle, He, Yuanjun, Kamenecka, Theodore M.
Publié dans Tetrahedron Lett (2016)

Cytochrome P450-Mediated Bioactivation of the Epidermal Growth Factor Receptor Inhibitor Erlotinib to a Reactive Electrophile

par Li, Xiaohai, Kamenecka, Theodore M., Cameron, Michael D.
Publié 2010

LXR-Mediated Inhibition of CD4(+) T Helper Cells

par Solt, Laura A., Kamenecka, Theodore M., Burris, Thomas P.
Publié 2012

Discovery of a Highly Selective CYP3A4 Inhibitor Suitable for Reaction Phenotyping Studies and Differentiation of CYP3A4 and CYP3A5

par Li, Xiaohai, Song, Xinyi, Kamenecka, Theodore M., Cameron, Michael D.
Publié 2012

Pharmacological modulation and genetic deletion of REV-ERBα and REV-ERBβ regulates dendritic cell development

par Amir, Mohammed, Campbell, Sean, Kamenecka, Theodore M., Solt, Laura A.
Publié dans Biochem Biophys Res Commun (2020)

Pharmacological repression of RORγ is therapeutic in the collagen-induced arthritis experimental model

par Chang, Mi Ra, Lyda, Brent, Kamenecka, Theodore M., Griffin, Patrick R.
Publié dans Arthritis Rheumatol (2014)

Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors

par Jain, Akansha, Kuryatov, Alexander, Wang, Jingyi, Kamenecka, Theodore M., Lindstrom, Jon
Publié dans J Biol Chem (2016)

ROR Inverse Agonist Suppresses Insulitis and Prevents Hyperglycemia in a Mouse Model of Type 1 Diabetes

par Solt, Laura A., Banerjee, Subhashis, Campbell, Sean, Kamenecka, Theodore M., Burris, Thomas P.
Publié dans Endocrinology (2015)

Suppression of atherosclerosis by synthetic REV-ERB agonist

par Sitaula, Sadichha, Billon, Cyrielle, Kamenecka, Theodore M., Solt, Laura A., Burris, Thomas P.
Publié dans Biochem Biophys Res Commun (2015)

Quantitative structural assessment of graded receptor agonism

par Shang, Jinsai, Brust, Richard, Griffin, Patrick R., Kamenecka, Theodore M., Kojetin, Douglas J.
Publié dans Proc Natl Acad Sci U S A (2019)

Methamphetamine Learning Induces Persistent and Selective Nonmuscle Myosin II-Dependent Spine Motility in the Basolateral Amygdala

par Young, Erica J., Lin, Hua, Kamenecka, Theodore M., Rumbaugh, Gavin, Miller, Courtney A.
Publié dans J Neurosci (2020)

Insular hypocretin transmission regulates nicotine reward

par Hollander, Jonathan A., Lu, Qun, Cameron, Michael D., Kamenecka, Theodore M., Kenny, Paul J.
Publié 2008

Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor

par Brust, Richard, Lin, Hua, Fuhrmann, Jakob, Asteian, Alice, Kamenecka, Theodore M., Kojetin, Douglas J.
Publié dans ACS Chem Biol (2017)

Efficient Methodology for the Synthesis of 3-Amino-1,2,4-triazoles

par Noël, Romain, Song, Xinyi, Jiang, Rong, Chalmers, Michael J., Griffin, Patrick R., Kamenecka, Theodore M.
Publié 2009

Correction: Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression

par Amador, Ariadna, Wang, Yongjun, Banerjee, Subhashis, Kamenecka, Theodore M., Solt, Laura A., Burris, Thomas P.
Publié dans PLoS One (2016)

Discovery of an intrasubunit nicotinic acetylcholine receptor–binding site for the positive allosteric modulator Br-PBTC

par Norleans, Jack, Wang, Jingyi, Kuryatov, Alexander, Leffler, Abba, Doebelin, Christelle, Kamenecka, Theodore M., Lindstrom, Jon
Publié dans J Biol Chem (2019)

Identification of a Selective RORγ Ligand that Suppresses T(H)17 cells and Stimulates T Regulatory Cells

par Solt, Laura A., Kumar, Naresh, He, Yuanjun, Kamenecka, Theodore M., Griffin, Patrick R., Burris, Thomas P.
Publié 2012

An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors

par Wang, Jingyi, Kuryatov, Alexander, Sriram, Aarati, Jin, Zhuang, Kamenecka, Theodore M., Kenny, Paul J., Lindstrom, Jon
Publié dans J Biol Chem (2015)

A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit

par Wang, Jingyi, Kuryatov, Alexander, Jin, Zhuang, Norleans, Jack, Kamenecka, Theodore M., Kenny, Paul J., Lindstrom, Jon
Publié dans J Biol Chem (2015)