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Identification of a Selective RORγ Ligand that Suppresses T(H)17 cells and Stimulates T Regulatory Cells
Nuclear Receptors (NRs) are ligand-regulated transcription factors, many of which are validated targets for clinical purposes. The retinoic acid receptor-related orphan nuclear receptors alpha and gamma t (RORα and RORγt) are considered the master regulators of development of T(H)17 cells, a subset...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448878/ https://ncbi.nlm.nih.gov/pubmed/22769242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb3002649 |
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