Identification of SR2211: a potent synthetic RORγ selective modulator

Nuclear receptors (NRs) are ligand-regulated transcription factors that display canonical domain structure with highly conserved DNA-binding and ligand-binding domains. The identification of the endogenous ligands for several receptors remains elusive or is controversial, thus these receptors are cl...

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Autori principali: Kumar, Naresh, Lyda, Brent, Chang, Mi Ra, Lauer, Janelle L., Solt, Laura A., Burris, Thomas P., Kamenecka, Theodore M., Griffin, Patrick R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331898/
https://ncbi.nlm.nih.gov/pubmed/22292739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200496y
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