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LXR-Mediated Inhibition of CD4(+) T Helper Cells

T(H)17 cells, which require the expression of both retinoic acid receptor-related orphan receptors α and γt (RORαand RORγt) for full differentiation and function, have been implicated as major effectors in the pathogenesis of inflammatory and autoimmune diseases. We recently demonstrated that the Li...

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Detalhes bibliográficos
Main Authors: Solt, Laura A., Kamenecka, Theodore M., Burris, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460920/
https://ncbi.nlm.nih.gov/pubmed/23029557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046615
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