Germinal centre alloantibody responses are mediated exclusively by indirect-pathway CD4 T follicular helper cells

The durable alloantibody responses that develop in organ transplant patients indicate long-lived plasma cell output from T-dependent germinal centres (GCs), but which of the two pathways of CD4 T cell allorecognition are responsible for generating allospecific T follicular helper (T(FH)) cells remai...

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Bibliografiske detaljer
Main Authors: Conlon, Thomas M, Saeb-Parsy, Kourosh, Cole, Jennifer L, Motallebzadeh, Reza, Qureshi, M Saeed, Rehakova, Sylvia, Negus, Margaret C, Callaghan, Chris J, Bolton, Eleanor M, Bradley, J Andrew, Pettigrew, Gavin J
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378630/
https://ncbi.nlm.nih.gov/pubmed/22323543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102830
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