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An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors
Neuronal nicotinic acetylcholine receptors containing α4, β2, and sometimes other subunits (α4β2* nAChRs) regulate addictive and other behavioral effects of nicotine. These nAChRs exist in several stoichiometries, typically with two high affinity acetylcholine (ACh) binding sites at the interface of...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4447965/ https://ncbi.nlm.nih.gov/pubmed/25869137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646786 |
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