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Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors

All nicotinic acetylcholine receptors (nAChRs) evolved from homomeric nAChRs in which all five subunits are involved in forming acetylcholine (ACh) binding sites at their interfaces. Heteromeric α4β2* nAChRs typically have two ACh binding sites at α4/β2 interfaces and a fifth accessory subunit surro...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jain, Akansha, Kuryatov, Alexander, Wang, Jingyi, Kamenecka, Theodore M., Lindstrom, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095401/
https://ncbi.nlm.nih.gov/pubmed/27645992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.749150
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