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N-arylsulfonyl indolines as RORγ agonists
The nuclear receptor RORγ (NR1F3) is a key regulator of inflammatory gene programs involved in T helper 17 (T(H)17) cell proliferation. As such, synthetic small molecule repressors (inverse agonists) targeting RORγ have been extensively studied for their potential as therapeutic agents for various a...
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| Veröffentlicht in: | ChemMedChem |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5158182/ https://ncbi.nlm.nih.gov/pubmed/27879053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600491 |
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