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Divergent Sequence Tunes Ligand Sensitivity in Phospholipid-regulated Hormone Receptors
The members of the NR5A subfamily of nuclear receptors (NRs) are important regulators of pluripotency, lipid and glucose homeostasis, and steroidogenesis. Liver receptor homologue 1 (LRH-1; NR5A2) and steroidogenic factor 1 (SF-1; NR5A1) have therapeutic potential for the treatment of metabolic and...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711333/ https://ncbi.nlm.nih.gov/pubmed/23737522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472837 |
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