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Targeting Orphan Nuclear Receptors for Treatment of Metabolic Diseases and Autoimmunity
The nuclear receptor (NR) superfamily is composed of 48 members in humans and includes receptors for steroid hormones, thyroid hormone, various lipids and oxysterols. This superfamily has been a rich source of drug targets for myriad diseases including inflammation, cancer, and metabolic disorders....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269034/ https://ncbi.nlm.nih.gov/pubmed/22284354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.12.011 |
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