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Identification of Bexarotene as a PPARγ Antagonist with HDX
The retinoid x receptors (RXRs) are the pharmacological target of Bexarotene, an antineoplastic agent indicated for the treatment of cutaneous T cell lymphoma (CTCL). The RXRs form heterodimers with several nuclear receptors (NRs), including peroxisome proliferator-activated receptor gamma (PPARγ),...
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| Publicado no: | PPAR Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586960/ https://ncbi.nlm.nih.gov/pubmed/26451138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/254560 |
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