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Identification and function of conformational dynamics in the multidomain GTPase dynamin

Vesicle release upon endocytosis requires membrane fission, catalyzed by the large GTPase dynamin. Dynamin contains five domains that together orchestrate its mechanochemical activity. Hydrogen–deuterium exchange coupled with mass spectrometry revealed global nucleotide‐ and membrane‐binding‐depende...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Srinivasan, Saipraveen, Dharmarajan, Venkatasubramanian, Reed, Dana Kim, Griffin, Patrick R, Schmid, Sandra L
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755114/
https://ncbi.nlm.nih.gov/pubmed/26783363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593477
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