Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

Voltage-gated KCNQ1 (Kv7.1) potassium channels are expressed abundantly in heart but they are also found in multiple other tissues. Differential coassembly with single transmembrane KCNE beta subunits in different cell types gives rise to a variety of biophysical properties, hence endowing distinct...

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Bibliographic Details
Main Authors: Yu, Haibo, Lin, Zhihong, Mattmann, Margrith E., Zou, Beiyan, Terrenoire, Cecile, Zhang, Hongkang, Wu, Meng, McManus, Owen B., Kass, Robert S., Lindsley, Craig W., Hopkins, Corey R., Li, Min
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666726/
https://ncbi.nlm.nih.gov/pubmed/23650380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300684110
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